Endocrine Abstracts

It has been shown that miR-107 regulates insulin sensitivity, but its status in severe insulin resistance (IR) patients has not been established. In this study, we investigated the expression of microRNA-107 in the sera from patients with clinically severe IR and its relationships with metabolic characteristics.Methods: The expression of microRNA-107 was detected in the sera of 30 clinically severe IR patients and 24 gender and age-matched control group ...

Pheochromocytoma (PCC) is a rare neuroendocrine tumor, mainly sporadic, many cases are discovered incidentally by computed tomography or magnetic resonance imaging of the abdomen. Malignancy in pheochromocytoma is difficult to diagnose microscopically. Therefore, only the presence of distant metastases, derived from pleomorphic chromaffin cells, is widely accepted as a criterion of malignancy (1)Case presentation: In March 2016, a 43 year old women prese...

Some patients with type 2 diabetes mellitus (T2DM) suffer from severe insulin resistance (IR). There is still a shortage of research analyzing these patients. Relation between IR and diabetes complications, risk of mortality has been poorly described in patients with T2DM.Objective: To evaluate the prevalence of microvascular and macrovascular complications, mortality in type 2 diabetes patients with severe insulin resistance.Metho...

Objective: Pregnancy in women with type I diabetes mellitus (T1DM) is associated with an increased risk of various obstetric complications. The purpose of this study was to evaluate relation of HbA1c, delivery age and various diabetes aspects on pregnancy outcome and gestation in women with T1DM.Methods: This was a cross-sectional study. A total of 48 women hospitalized to the Hospital of Lithuanian University of Health Sciences Kauno klinikos Endocrinol...

Objective: The aim of the study was to determine frequency of insulin resistance, in individuals with type 1 diabetes mellitus and the link between insulin resistance and cardiovascular disease, sex hormones. The task of the research is to determine the frequency of insulin resistance among people with diabetes mellitus type 1. To determine association between eGDR and age, sex, cardiovascular disease, chronic complications of diabetes and sex hormones. To determine associatio...

Hashimoto encephalopathy (HE) is a rare and steroid responsive encephalopathy associated with autoimmune thyroiditis (1). Patients with Hashimoto encephalopathy may present with a variety of neuropsychiatric signs (2). 68-year old woman was admitted to the Neurology Department, of Hospital of Lithuanian University of Health Sciences, Kauno klinikos (HLUHS KK), due to disorder of consciousness of uncertain aetiology in August 2016. The signs of motor dysfunction, generalized ri...

Despite that the thyroid gland is one of the most vascular organs of the body but thyroid gland is an uncommon site for metastasis [1]. It represents less than 4% of thyroid malignancy in clinical and surgical studies [2, 3]. 58-year-old male, a prior smoker, was diagnosed with nonsmall cell lung cancer T4N3M1 St IV, histopathological findings - infiltrative adenocarcinoma, G1. About eight months he was treated with chemotherapy. At the beginning of the disease, the patient wa...

Some patients with type 2 diabetes mellitus (T2DM) suffer from severe acquired insulin resistance (IR). There is still a shortage of research analyzing the T2DM patients with severe IR and identifying their risk factors.Aim: To evaluate how selected sociodemographic and metabolic factors are linked to severe IR among patients with T2DM.Methods: It was a case control study. If T2DM patients received high insulin doses (>1 IU/kg/...